Dr. Jay Wrigley, NMD · Root Cause Journal
Hormones, Metabolism & Longevity
Clinical insights on the hormonal patterns most doctors miss — written for patients who are done with generic answers.
Cortisol Dysregulation: Hidden Driver of Midlife Fatigue
Chronic cortisol dysregulation drives fatigue, belly fat, and poor sleep in midlife. Here's how to identify and correct it clin...
Apr 10, 2026
Estrogen Dominance After 40: It's Not Too Much Estrogen
Estrogen dominance is rarely about too much estrogen—it's about progesterone deficiency. Learn the real cause and clinical corr...
Apr 10, 2026
Insulin Resistance in Women Over 40: Beyond Calories
Why does 'eat less, move more' stop working after 40? Insulin resistance in women is the missing piece. Here's the clinical exp...
Apr 10, 2026
Cortisol Burnout: Exhaustion, Belly Fat & Brain Fog
Cortisol burnout creates a specific pattern: wired but tired, belly fat, poor sleep, and brain fog. Here's how to identify and ...
Apr 10, 2026
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