

B Activ® 90 Capsules
B Activ® — Dr. Jay Wrigley's Active B-Vitamin Complex for Methylation and Energy
B Activ® provides the active, methylated forms of the B-vitamin complex — a critical distinction that Dr. Jay Wrigley emphasizes in his clinical practice. As an NMD and Functional Medicine Doctor, Dr. Wrigley routinely identifies MTHFR gene variants and methylation pathway inefficiencies in patients presenting with fatigue, mood disorders, cardiovascular risk, and hormonal imbalance. Standard B-vitamin supplements containing folic acid (the synthetic, non-methylated form) are poorly utilized by these patients and may actually worsen their methylation burden.
In the LCHPMF™ framework, methylation is a foundational biochemical process that affects hormone metabolism, neurotransmitter synthesis, DNA repair, and detoxification. B Activ® provides methylfolate, methylcobalamin, and the full active B-complex in forms that bypass common genetic bottlenecks and support optimal methylation regardless of MTHFR status.
Clinical context: Dr. Wrigley recommends B Activ® for patients presenting with the Cortisol Dominant, Mood-Driven, and Thyroid Sluggish archetypes, as well as any patient with known MTHFR variants, elevated homocysteine, or a history of poor response to standard B-vitamin supplementation.
About Dr. Jay Wrigley, NMD
Dr. Jay Wrigley is a licensed Naturopathic Medical Doctor (NMD) and Functional Medicine practitioner with over 30 years of clinical experience specializing in hormone optimization, metabolic health, and longevity medicine. He is the creator of the LCHPMF™ (Lifestyle, Circadian, Hormonal, Psychological, Metabolic, and Functional) clinical framework — a comprehensive, root-cause approach to understanding why the body's hormone and metabolic systems shift with age, stress, and lifestyle. Dr. Wrigley's protocols are grounded in peer-reviewed research, clinical outcomes, and his proprietary 16-archetype pattern recognition system, which identifies the specific hormonal and metabolic patterns driving each patient's symptoms.
This product is available through Dr. Wrigley's professional dispensary. Use code DRWRIGLEY at Wholescripts or access his curated Fullscript dispensary at fullscript.com/welcome/drjaywrigley. These are physician-curated recommendations, not medical advice. Always consult your licensed healthcare provider before starting any supplement protocol.
When registering, use referral code DRWRIGLEY and last name WRIGLEY.
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When registering, use referral code DRWRIGLEY and last name WRIGLEY.
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